FLAVOXALE® is a unique ingredient derived from the combination of an exclusive propolis extract (M.E.D. propolis), manuka honey and manuka essential oil.

Propolis is a resinous matrix that bees (Apis mellifera) collect from gems, exudates and plants, resulting in a heterogeneous mixture of many substances; among the most representative metabolites of propolis there are flavonoids, terpenoids, phenolic acids, phenolic esters and sugars in different proportions, that are responsible of the properties namely antioxidant, anti-inflammatory and antimicrobial.

Manuka tea trees (Leptospermum scoparium) are small trees or shrubs distributed throughout New Zealand in widely varying climates, altitudes, and population densities. Use of the bark, leaves, sap, and seed capsules of these plants is reported in New Zeland’s memories, especially in beverage supplements and in pharmaceutical and medicinal preparations. The most important products derived from Manuka tea trees are Manuka honey and Manuka essential oil, both alone showing a great anti inflammation and anti bacterial activity.

Manuka honey is rich in MethylGlyoxale (MGO), the compound primarily responsible for its Non-Peroxide Activity (N.P.A.), which forms from the nectar-derived compound, dihydroxyacetone (DHA), during the ripening of honey.

Manuka essential oil is reach in terpenes (primary monoterpenes, sesquiterpenes, methyl cinnamate and triketones) that can be considered responsible for its activity through activation of several pathways, whose results is the inhibition on inflammation induced by LPS

The combination of those natural ingredients and M.E.D. technology creates FLAVOXALE®: a water soluble, free flowing powder, ideal for formulation of both solid and liquid dosage forms as well as any kind of food products.

With documented and proven functional activities such as antibacterial, antinflammatory and wound-healing, it offers an exotic chance to enrich the content and image of food and pharmaceutical products in an innovative way.